cis-eQTLs

This page contains the cis-eQTL results. The statistically significant cis-eQTLs and SMR-prioritised genes for several traits are browsable, the other files can be downloaded.

Changelog
2019-12-23: Cis-eQTLs are now updated to have a 2-cohort filter: every cis-eQTL must be tested in at least 2 cohorts to be reported. The files now also include Bonferroni-adjusted p-values.
2018-10-19: Initial data release

Significant cis-eQTLs

SNP Gene Allele
P-value ID Chr Pos (hg19) ID Symbol Chr Pos (hg19) Z-score Assessed Other Nr Cohorts Nr Samples FDR
P-value ID Chr Pos ID Symbol Chr Pos Z-score Assessed Other Nr Cohorts Nr Samples FDR

SMR

Summary statistics based Mendelian Randomisation (SMR) is a statistical approach to infer putatively causal genes. Here you can download the cis-eQTL results in SMR format, as well as the results for the traits that we have looked at in the manuscript.

Allele frequencies

Download the allele frequencies for all tested SNPs here:
Allele frequencies based on 26,609 eQTLGen samples (excluding FHS)
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